Courses a.a. 2020/2021

1. Science Communication. How to communicate the impact of scientific projects to different audiences

20 hours, Dr. Elisabetta Mutto-Accordi,

March (16:00-18:00): zoom conference, 3,12,17,24,31

April: (16:00-18:00): zoom conference 7,17,21,28

April: (16:00-18:00): zoom conference 7,14,21,28

May (16:00-18:00): zoom conference 5

The learning program focuses on simulations and exercises in the classroom and on direct involvement of participants. On this base, PhD students will practice changing their communicative approach using also diverse range of media. They will develop basic skills to convey the content of their work at a level that a general audience can understand.

2. Prof. Paolo Bernardi, Pathophysiology of mitochondria: From energy conservation to disease pathogenesis and therapy

10 hours, Prof. Paolo Bernardi

May 10-12-13-14 (room H mezzanine floor Vallisneri Building), May 11 (room L mezzanine floor Vallisneri Building),


1) The basic features of mitochondria and their function

2) The mechanism of energy conservation and its implications for cation transport (K+, Na+, and Ca2+)

3) Overview of the role of mitochondria in cell death

4) Critical assessment of the permeability transition and its role in disease pathogenesis

5) Recent progress in the mitochondrial therapy of muscular dystrophies

3. Neurodegenerative diseases: Epidemiology, genetics and pathogenesis of brain misfolding diseases

10 hours, Prof. Maria Pennuto

May 24-25-26-27-28

1) Principles of neurodegeneration

2) Alzheimer disease: clinical aspects, pathology, genetics

3) Parkinson disease: clinical aspects, pathology, genetics

4) Repeat expansion disorders: Loss of function, RNA-mediated gain of function andprotein-mediated gain of function, Polyglutamine diseases

5) The genetics of ALS: Focus of RNA- and protein-mediated motor neuron degeneration

4. A journey with the cytotoxic lymphocytes

10 hours, Dott. Denis Martinvalet

May 17-18-19-20-21, 16:00-18:00 zoom conference

1) Self and Non-self for the cytotoxic lymphocytes: A general introduction to basic immunology.

2) Cytotoxic lymphocytes in the body: Histology of the lymphoid tissues.

3) Development, function and pathology of cytotoxic lymphocytes.

4) Mechanisms of lymphocyte cytotoxicity.

5) Cytotoxic lymphocytes in the clinic.

5. Neuromuscular system plasticity to use, disuse and ageing

10 hours, Prof. Marco Narici:

June: 7-8-9-10-11, 16:00-18:00, zoom conference

1) Skeletal Muscle: Structure and Function

2) Motor units and force generation

3) Neuromuscular adaptations with increased use

4) Neuromuscular adaptations with inactivity

5) Neuromuscular changes with ageing

6. Post-translation modifications of proteins (PTMs): how to survive in a dense forest

10 hours, Proff. Maria Ruzzene, Mauro Salvi, Christian Borgo:

June: 14-15-16-17-18, 16:00-18:00, zoom conference

1. PTMs: an overview

2. Protein phosphorylation: how, when, why

3. How to modulate PTMs by using inhibitors and activators

4. Phospho-site identification and characterization

5. Workshop: see if PTMs are involved in your research at all. Practical cases proposed by the students

7. Satistica Methods

Davide Risso - Department of Statistical Sciences

February 2021

1. Introduction to statistics, the R programming language, and
reproducible research

2. Introduction to probability and statistical inference

3. Parameter estimation

4. Statistical inference

5. Regression models

6. Regression models





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